Research

Liquid Biopsies

Research based on circulating tumour cells (CTCs) and circulating tumour- and free- DNA (ctDNA, cfDNA) has generated much interest, opening the potential of liquid biopsies, as an -non-invasive- alternative to conventional tissue biopsies; thus allowing a better routine patient monitoring, and robust genetic characterisation of the cancer. The concept of tumour and cancer profiling from liquid biopsies is an exciting field, opening the potential to solve many issues currently surrounding cancer diagnosis/prognosis and treatment. In our lab, we have teamed up with numerous hospitals nationally and internationally, to study the potential clinical benefits of liquid biopsies.

Metabolic Syndrome & Cancer

Excess body fat increases the risk of a number of cancers. Work led by Prof. Chatterjee has shown that obesity is the biggest risk factor for endometrial cancer. In our group, we are studying the effects of adipokines (cytokines secreted from adipose tissue) in health and disease, using in vitro models and neural network algorithms.

Endocrine Disrupting Chemicals

Endocrine Disrupting Chemicals (EDCs) are chemicals or mixtures that are found in various materials such as pesticides, plastics, industrial chemicals, and personal care products. EDCs have been associated with obesity, diabetes, breast cancer, and altered reproductive function. We are studying the effects of EDCs in human reproductive tissues.

Artificial Intelligence in Health and Disease

Artificial intelligence (AI) is transforming healthcare by enhancing diagnostic accuracy, accelerating drug discovery, and enabling personalized medicine. We are collaborating with leading authorities in the field, with the aim to improve cancer detection and response to treatments.

Space Biology

As humanity prepares for long-duration space missions (including lunar bases, and Mars exploration) understanding and sustaining reproductive health becomes a critical frontier. In our lab we assess the effects of microgravity in human placentation.

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